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application methods
The pesticide application method you choose depends on the nature and habits of the target pest, the properties of the pesticide, the suitability of the application equipment, and the cost and efficiency of alternative methods. Your choice is often predetermined by one or more of these factors. Follow label direction for volume recommendations and application rates based on the pest to be controlled and utilize appropriate application tips on equipment.
What is Bromethalin?
Bromethalin was developed and released in 1985 to combat a world-wide problem of rodent resistance to warfarin-like anticoagulant rodenticides. Bromethalin is not an anticoagulant but is a highly potent rodenticide that provides a lethal dose to rodents in a single feeding. Death occurs within 24 to 36 hours after ingestion.
How does Bromethalin work? (Mode of Action)
Its mechanism of action is to uncouple oxidative phosphorylation in the mitochondria of the central nervous system. This leads to a decreased production of ATP. Low levels of ATP inhibit the activity of the Na/K ATPase and lead to a subsequent buildup of cerebral spinal fluid and vacuolization of myelin. The increased CSF results in high intracranial pressure, causing damage to nerve axons, inhibiting neural transmission and leading to paralysis, convulsions and death.
Keep out of reach of children.
Always check the label for warnings and instructions for use.
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